Below is a list and brief outline of NSARI's current projects;
Sugammadex and Postoperative Respiratory Complications
A retrospective case review of over 1200 patients comparing rates of recovery room and in hospital respiratory complications before and after the introduction of the routine use of sugammadex, a novel anaesthetic reversal agent. RNS was one of the first hospitals in the world to begin using this new drug routinely. (Published October 2016) This will be followed by a multi-centre, randomised blinded trial to investigate the results, which has ethics approval and will commence in March/April 2017.
Recovery Outcome Auditing
Ongoing quality improvement where individual anaesthetists and the department as a whole are measured with respect to post operative complications, nausea and vomiting and pain outcomes.
Intraoperative Neurophysiological Monitoring
A prospective audit of the implications of Intraoperative Neurophysiological Monitoring on outcome during neurosurgical procedures which threaten the integrity of neural structures. Anaesthesia-led Intraoperative Neurophysiological Monitoring is a specialty service provided through Royal North Shore and North Shore Private Hospital and currently represents the cutting edge of neuroanesthesia services.
Sugammadex and Postoperative Cognitive Function
An NSARI designed and led randomised, controlled trial on the impact of sugammadex on early postoperative cognitive function. This has special implications for day surgery and day stay surgical patients and their return to normal function.
Management of fractured neck of femur patients and postoperative outcomes
In association with the NSW Special Committee Investigating Deaths Under Anaesthesia (SCIDUA), a retrospective analysis of cases reported to SCIDUA is being analysed looking for patterns leading to mortality. This is being used to design a prospective database to further delineate factors that can be used to predict morbidity and improve the safety of anaesthesia for patients with hip fractures.
Multicentre ANZCA Trials
We are currently funding and recruiting staff to allow us to be involved with a number of ANZCA supported multicentre trials. This will improve our research infrastructure and experience with large scale medical research.
Intrathecal Morphine in Total Knee Replacement
An NSARI designed and led prospective randomised controlled trial looking at differences in anaesthetic and functional outcomes following the addition of intrathecal morphine to a standardised anaesthetic regime in primary unilateral total knee replacement